Journal article
Plasma prolactin and postmenopausal breast cancer risk: a pooled analysis of four prospective cohort studies.
Jacob K Kresovich, Catherine Guranich, Serena Houghton, Jing Qian, Micheal E Jones, Maegan E Boutot, Mitch Dowsett, A Heather Eliassen, Montserrat Garcia-Closas, Peter Kraft, Aaron Norman, Michael Pollak, Sabina Rinaldi, Bernard Rosner, Minouk J Schoemaker, Christopher Scott, Anthony J Swerdlow, Roger L Milne, Shelley S Tworoger, Celine M Vachon Show all
Breast Cancer Res | Published : 2024
Abstract
BACKGROUND: Prolactin, a hormone produced by the pituitary gland, regulates breast development and may contribute to breast cancer etiology. However, most epidemiologic studies of prolactin and breast cancer have been restricted to single, often small, study samples with limited exploration of effect modification. METHODS: The Biomarkers in Breast Cancer Risk Prediction consortium includes 8,279 postmenopausal women sampled from four prospective cohort studies, of whom 3,441 were diagnosed with invasive breast cancer after enrollment. Prolactin concentrations were measured for all study participants on plasma samples collected when all women were postmenopausal and before any breast cancer d..
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